A three-days workshop that will bring together most of the international leaders on Systems Biology
Galleria delle Scienze
UNIVERSITA’ degli Studi di Milano-Bicocca
Piazza della Scienza, 2
Milano, Italy
14.00
Registration
14.30
OPENING ADDRESSES
Chair:Lilia Alberghina, University of Milano-Bicocca, Milan, Italy
• Marcello Fontanesi, Rector, University of Milano-Bicocca, Milan, Italy
• Luigi Rossi Bernardi, Councillor for Research, Innovation and Human Resources, Municipality of Milan, Milan, Italy
• Rita Levi-Montalcini, Nobel Laureate, President of European Brain Research Institute, Rome, Italy Inaugural Address
Chair: Francesco Nicotra, Dean, Faculty of Mathematics, Physics and Natural Sciences, University of Milano-Bicocca, Milan, Italy
15.00
Lorenzo Pinna
- University of Padova, Italy Protein kinase CK2: a master regulator of cell functions (and dysfunctions)
15.45
Thomas Höfer - German Cancer Research Center (Dkfz) - Bioquant, Heidelberg, Germany
Multi-site phosphorylation in cell regulation
Dynamic trade-offs in DNA replication and repair
16.30
Philippe Selenko - Leibniz Institute of Molecular Pharmacology (FMP Berlin), Berlin, Germany Instant kinase activity profiling by high-resolution NMR spectroscopy
17.15
Coffee break
17.45
Gustav Ammerer - Department of Biochemistry and Cell Biology, Max.F.Perutz Laboratories, University of Vienna, Austria Mass Spectrometry analysis of protein phosphorylation
Chair: Lilia Alberghina, University of Milano-Bicocca, Milan, Italy
18.30
Cecilia Saccone - ITB-CNR, University of Bari, Italy New approaches in the study of mitochondrial genome evolution in Metazoaes
ITALBIONET REPORTS Chair: Cristina Messa, Dept. of Medical Surgery, University of Milano-Bicocca, Milan, Italy
09.00
Luciano Milanesi - Inst. of Biomedical Technologies, CNR Milan, Italy
Challenges in Biomedical Complex Systems
09.20
Giuliano Armano - DIEE – Dept. of Electrical and Electronic Engineering, University of Cagliari, Italy Encoding techniques and neural network architectures for predicting protein secondary structures
09.40
Giancarlo Mauri - Dept. of Information Technology, Systems and Communication, University of Milano-Bicocca, Italy A study of particle swarm optimization for parameters estimation in biochemical systems
10.00
Gastone Castellani - Dept. of Physics, University of Bologna, Italy Master equation modelling and measurements for systems biology: a unified approach to selected medical problems
10.20
Marco Vanoni - Dept of Biotechnology and Biosciences, University of Milano-Bicocca, Italy The network controlling entrance into S phase and its emergent properties
10.40
Diego di Bernardo - Telethon Institute of Genetics & Medicine (TIGEM), Italy Systems and synthetic biology: reverse engineering and modelling molecular pathways
11.00
Coffee break
11.20
Valeria Poli - Dept. of Genetics, Biology and Biochemistry, Molecular Biotecnology Center, University of Turin, Italy
Genome-wide discovery of functional transcription factor binding sites by comparative genomics: the case of Stat3.
11.40
Francesco Archetti - Consorzio Milano Ricerche, University of Milano-Bicocca, Italy
A Markov base classification and treatment of the anticoagulant patient
12.00
Riccardo Bellazzi - Dept. of Informatics and Systems, University of Pavia, Italy
Clinical Bioinformatics: methods and tools for integrating molecular biology at the bedside
12.20
Claudio Franceschi - Dept. of Medicine, University of Bologna, Italy
The aging human liver: a comprehensive "omics" approach
12.40
Ferdinando Chiaradonna - Dept of Biotechnology and Biosciences, University of Milano-Bicocca, Italy
Nutritional modulation of transformed phenotype: an integrated “omics” approach
13.00
Alexander Kel - BIOBASE GmbH, Wolfenbuettel, Germany
Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia
Net2Drug: Modeling apoptosis to survival balance in tumor cells
13.30
Lunch and Poster Session
15.15
Oral Presentations
1.
Pasqualina D’Ursi – CNR-ITB, Segrate (MI), Italy Reverse Molecular Docking and Pathway Analysis for the Identification of Protein Targets and Pathways of Endocrine Disruptor Bisphenol A
2.
Paolo Tortora – Dept of Biotechnology and Biosciences, University of Milano-Bicocca, Italy A Possible Role for Ataxin-3 in Directing Aggregated Protein to Degradation
3.
Stefania Brocca - Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy Intrinsic Structure of an Intrinsically-Disordered Protein: the Yeast Cyclin-Dependent Kinase Inhibitor Sic1
4.
Maria Luisa Genova – Dipartimento di Biochimica, Alma Mater Studiorum, Università di Bologna, Italy Characterisation of the Supramolecular Organisation of the Mitochondrial Respiratory Chain: a Methodological Approach by Metabolic Control Analysis
5.
Elena Papaleo – Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy Regulation of E2 Ubiquitin-conjugating Enzymes by Phosphorylation: a Molecular Dynamics Investigation
6.
Paolo Tieri – L. Galvani Interdept Center, University of Bologna, Italy Reconstruction and Analysis of the NF-?B Pathway Interactome
Ferdinando Di Cunto – Dept. of Genetics, Biology and Biochemistry, Molecular Biotecnology Center, University of Turin, Italy Reverse Conserved Coexpression Networks: Form Functional Prediction to Disease Gene Prioritization A
2.
Ilaria Giordani - University of Milano-Bicocca, Milan, Italy Discovering Relationships Among Human Cancer, Gene Expression Profile And Drug Responses: A Relational Clustering Approach
3.
Francesca Cordero - Department of Computer Science and Department of Clinical and Biological Sciences, University of Turin, Italy An Intuitive Object-oriented Methodology to Model Biological Pathways
4.
Raffaella Rizzi - Department of Informatics, System and Communication (D.I.S.Co.) EST Clustering for Gene Identification
5.
Antonella Farinaccio - Department of Informatics, Systems and Communication (D.I.S.Co.), University of Milano-Bicocca, Milan, Italy Genetic Programming for Survival Prediction in Breast Cancer
6.
Italo Zoppis - Department of Informatics, Systems and Communication, University of Milano-Bicocca A Mutual Information Approach to Data Integration for Alzheimer’s Disease Patients
7.
Pasquale Palumbo - National Research Council, IASI “A. Ruberti” A Mathematical Scheme for Network Motifs Identification
11.00
Coffee break
11.30
8.
Roberta Alfieri – Institute for Biomedical Technologies-CNR, Segrate (MI), Italy Towards an Integrative Model for the Calcium Role in the Neurodegenerative Diseases
9.
Anna Maria Colangelo - Laboratory of Neuroscience “R. Levi-Montalcini”, Dept. of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy Role of Endogenous NGF in Modulation of Neuro-glial Network in the Spinal Cord of a Rat Model of Neuropathic Pain
10.
Florian Lamprecht - German Cancer Research Center, Heidelberg, Germany Kinetic Design of Interferon/Stat1 Signalling
11.
Enzo Martegani - Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy Simulation of the Ras/cAMP/PKA Pathway in Budding Yeast Evidences the Presence of Stable Oscillatory States
12.
Ettore Mosca - Institute for Biomedical Technologies-CNR, Segrate (MI) Identification of the Biological Processes in Fibroblast Cell Development by Differential Expression and Pathway Analysis
13.
Anneke Brümmer - German Cancer Research Center, Heidelberg, Germany
Systems Analysis of DNA Replication in Budding Yeast
14.
Danilo Porro - Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
From Modelling to Industrial Strain Improvement
15.
Josè Manuel Zaldivar-Comenges - European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Ispra (VA), Italy
Analysis of Toxicity Effects from Molecular to Population Level: Cyanobacteria Circadian Oscillator Case Study
13.00
Lunch and Poster Session
15.00
Anna Tramontano - Dept. of Biochemical Sciences “Rossi Fanelli”, University of Rome “La Sapienza”, Rome, Italy
Homo sapiens and its parasites: a systems biology approach
15.20
Oral Presentations Chair: Nicola Porro, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy
16.
Massimo La Rosa – ICAR-CNR e (DINFO) University of Palermo,Italy A Decision Support System for Reverse Engineering Gene Regulatory Networks
17.
Giovanni Felici - Istituto di Analisi dei Sistemi ed Informatica, CNR, Rome, Italy Integer and Logic Programming for Knowledge Extraction and its Application to Biological Data
18.
Daniel Remondini - Department of Physics, University of Bologna D-net: a Network Approach for High-throughput Classification Problems
16.00
‘YOUNG INVESTIGATOR AWARD’ Ceremony
16.15
Closing
Organizing Committee:
Lilia Alberghina,
Luciano Milanesi,
Marco Vanoni
